New Thiazolidine-4-ones of Ferulic Acid with Antioxidant Potential
نویسندگان
چکیده
New thiazolidine-4-one derivatives of ferulic acid have been synthesized in one step ("one-pot") by cyclization of ferulic acid hydrazide with different aromatic aldehydes and mercaptoacetic acid. The structure of the synthesized compounds was proved by infrared (IR) and nuclear magnetic resonance (H-NMR) spectroscopy. The in vitro antioxidant potential of the synthesized compounds was evaluated according to the 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2’-azinobis-(3ethylbenzothiazoline-6-sulfonic acid (ABTS) radical scavenging assays. Some of synthesized compounds showed a good antioxidant activity which supports the favourable influence of the structural modulation on the antioxidant effects of the ferulic acid.
منابع مشابه
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